Nioxin Hair Fall Defense Shampoo removes build-up and is clinically proven to grow stronger hair from the root. 93 Percent of people have less hair loss² and visible results in 12 weeks 3. The shampoo deeply cleanses your scalp, removing impurities and excess oil. It's formulated with a powerful blend of niacinamide, caffeine, lauric acid and SANDALORE. Together, these ingredients work to help stimulate hair follicles and nourish the hair. To use, massage shampoo on to scalp and hair for 2 minutes. Rinse thoroughly. Use daily for best results. Not a hair regrowth product. In a 48 week clinical study among 30 consumers with hair loss. After a 12 week clinical study among 30 consumers with hair loss.