Dihydroberberine is a patented ingredient being referred to as "super berberine" since preliminary research shows it to be 5x more effective than standard berberine. Since the effective dose of Dihydroberberine is so low, many users report experiencing far less side effects when compared to berberine. For best results, one capsule should be taken with (or immediately after) breakfast, lunch, and dinner. Double Wood's dihydroberberine is encapsulated and tested in the USA from globally sourced ingredients, Gluten Free, Vegan Safe, and Non GMO. Each bottle contains 60 capsules of 100mg per capsules.