Follows the journey of a time traveler from the post-apocalyptic future who appears in present day on a mission to locate and eradicate the source of a deadly plague that will nearly destroy the human race. "12 Monkeys" will continue the journey of James Cole (Aaron Stanford), a man sent back in time to eradicate the source of a deadly plague, and his partner, brilliant virologist Dr. Cassandra Railly (Amanda Schull). While attempting to untangle an insidious conspiracy that's been spun throughout centuries, the duo embark on a desperate search across time to find the man responsible for the apocalypse - a time traveler who calls himself the Witness.